Which disease is associated with the manifestation of "ear fullness" and fluctuating hearing loss?

Meniere's disease is indeed associated with the symptoms of "ear fullness" and fluctuating hearing loss. This condition is characterized by episodes of vertigo, tinnitus (ringing in the ears), and a sensation of fullness or pressure in the affected ear. The fluctuating nature of the hearing loss in Meniere's disease is one of its hallmark features, often resulting in periods of normal hearing between attacks.

The underlying mechanism involves an abnormal accumulation of fluid in the inner ear, which affects the balance and hearing structures. This fluid buildup can lead to increased pressure, causing the sensation of fullness, while also impacting the auditory structures, leading to fluctuating hearing capabilities.

In contrast, acute otitis externa typically presents with ear pain, discharge, and outer ear canal involvement, rather than the specific combination of fullness and fluctuating hearing loss. Conductive hearing loss usually results from issues in the outer or middle ear affecting sound transmission, rather than fluctuating symptoms. Presbycusis, or age-related hearing loss, generally leads to a gradual, progressive loss of hearing rather than the episodic nature associated with Meniere's disease.